Lethargy after Dexamethasone in dogs

831 reports to the FDA describe lethargy in dogs given Dexamethasone. That is 31% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

831Reports
77%Marked serious
18%Recovered
29%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
331 45%
1–2 days
124 17%
3–7 days
78 11%
1–4 weeks
87 12%
Over a month
119 16%

How the animals did

Recovered
144 17%
Recovered with lasting effects
3 0.4%
Still unwell when reported
346 42%
Died
126 15%
Euthanised
119 14%
Not known
93 11%

Problems reported at the same time

Age of the animals

Under 1 year
85
1–3 years
259
4–7 years
227
8–11 years
188
12+ years
66

About this medicine

Dexamethasone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Dexamethasone cause lethargy in dogs?
831 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Dexamethasone in dogs · Medicines most reported with lethargy