Dexamethasone + Neomycin + Polymyxin B side effects in dogs

161 reports sent to the FDA between 2003 and 2026 involve Dexamethasone + Neomycin + Polymyxin B in dogs. The most reported problems were vomiting, loss of appetite, lethargy. 47% were marked serious, and where it was recorded, signs eased after stopping the medicine in 0% of cases.

161Reports
47%Marked serious
4.3%Only medicine involved
39%Recovered
9.3%Died or euthanised
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About this medicine

Dexamethasone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Most reported side effects

59 37%
29 18%
Kidney problems
18 11%
Itching
16 9.9%
Ocular discharge
16 9.9%
Blood problems
15 9.3%
Skin redness
14 8.7%
Diarrhea
13 8.1%
Conjunctivitis
13 8.1%
Corneal ulcer
13 8.1%
Eye disorder (for photophobia see 'neurological')
12 7.5%
Swelling
12 7.5%
Eye or vision problems
10 6.2%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't work as expected
14 8.7%
Didn't stop worms
7 4.3%
Didn't prevent heartworm
2 1.2%
Didn't stop fleas
1 0.6%

How soon problems started

Same day
24 20%
1–2 days
13 11%
3–7 days
8 6.7%
1–4 weeks
18 15%
Over a month
56 47%

Time from the first dose to the first sign, where both dates were reported (119 reports).

How the animals did

Recovered
58 36%
Recovered with lasting effects
5 3.1%
Still unwell when reported
32 20%
Died
2 1.2%
Euthanised
13 8.1%
Not known
51 32%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other corticosteroids for dogs