Excessive urination after Prednisone in dogs

The FDA has received 460 reports of excessive urination in dogs after Prednisone. That is 5.1% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

460Reports
65%Marked serious
14%Recovered
10%Died or euthanised
19 daysTypical onset
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How soon it started

Same day
43 13%
1–2 days
32 9.6%
3–7 days
44 13%
1–4 weeks
96 29%
Over a month
118 35%

How the animals did

Recovered
56 12%
Recovered with lasting effects
7 1.5%
Still unwell when reported
168 37%
Died
16 3.5%
Euthanised
32 7.0%
Not known
181 39%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
80
4–7 years
156
8–11 years
142
12+ years
67

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause excessive urination in dogs?
460 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 19 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

All reported side effects of Prednisone in dogs · Medicines most reported with excessive urination