Walking difficulty after Praziquantel + Pyrantel in dogs

26 reports to the FDA describe walking difficulty in dogs given Praziquantel + Pyrantel. That is 0.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports

77%Marked serious

31%Recovered

7.7%Died or euthanised

Same dayTypical onset

How soon it started

Same day

16 67%

1–2 days

6 25%

3–7 days

2 8.3%

1–4 weeks

0 0.0%

Over a month

0 0.0%

How the animals did

Recovered

8 31%

Died

1 3.8%

Euthanised

1 3.8%

Not known

16 62%

Problems reported at the same time

12 46%

12 46%

7 27%

7 27%

5 19%

4 15%

4 15%

3 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause walking difficulty in dogs?: 26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Walking difficulty with similar medicines

Walking difficulty after Pyrantel + Sarolaner (Simparica Trio) 207 reports · 0.4% of its reports
Walking difficulty after Fenbendazole 33 reports · 0.6% of its reports
Walking difficulty after Pyrantel 23 reports · 0.5% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with walking difficulty