Eye or vision problems after Praziquantel + Pyrantel in dogs

The FDA has received 28 reports of eye or vision problems in dogs after Praziquantel + Pyrantel. That is 0.8% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

28Reports

79%Marked serious

29%Recovered

21%Died or euthanised

Same dayTypical onset

How soon it started

Same day

12 52%

1–2 days

6 26%

3–7 days

0 0.0%

1–4 weeks

3 13%

Over a month

2 8.7%

How the animals did

Recovered

7 25%

Recovered with lasting effects

1 3.6%

Still unwell when reported

3 11%

Died

6 21%

Not known

11 39%

Problems reported at the same time

8 29%

8 29%

7 25%

7 25%

6 21%

6 21%

6 21%

6 21%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause eye or vision problems in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eye or vision problems with similar medicines

Eye or vision problems after Pyrantel + Sarolaner (Simparica Trio) 152 reports · 0.3% of its reports
Eye or vision problems after Febantel + Praziquantel + Pyrantel (Drontal Plus) 21 reports · 0.3% of its reports
Eye or vision problems after Fenbendazole 47 reports · 0.8% of its reports
Eye or vision problems after Pyrantel 51 reports · 1.1% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with eye or vision problems