Lymphopenia after Polysulfated Glycosaminoglycan in dogs

The FDA has received 50 reports of lymphopenia in dogs after Polysulfated Glycosaminoglycan. That is 0.9% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause lymphopenia in dogs?

50 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 40 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lymphopenia with similar medicines

• Lymphopenia after Melarsomine (Immiticide) 43 reports · 0.2% of its reports
• Lymphopenia after Diphenhydramine 75 reports · 1.6% of its reports
• Lymphopenia after Butorphanol 44 reports · 1.0% of its reports
• Lymphopenia after Cefpodoxime 54 reports · 1.3% of its reports
• Lymphopenia after Tramadol 62 reports · 1.6% of its reports
• Lymphopenia after Florfenicol + Mometasone + Terbinafine 21 reports · 0.6% of its reports
• Lymphopenia after Propofol 24 reports · 0.8% of its reports
• Lymphopenia after Isoflurane 29 reports · 1.0% of its reports
• Lymphopenia after Cephalexin 30 reports · 1.1% of its reports
• Lymphopenia after Atipamezole 22 reports · 0.8% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with lymphopenia