Hyperglycaemia after Polysulfated Glycosaminoglycan in dogs

58 reports to the FDA describe hyperglycaemia in dogs given Polysulfated Glycosaminoglycan. That is 1.1% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

58Reports

64%Marked serious

21%Recovered

33%Died or euthanised

12 daysTypical onset

How soon it started

Same day

8 24%

1–2 days

4 12%

3–7 days

4 12%

1–4 weeks

5 15%

Over a month

13 38%

How the animals did

Recovered

10 17%

Recovered with lasting effects

2 3.4%

Still unwell when reported

11 19%

Died

9 16%

Euthanised

10 17%

Not known

16 28%

Problems reported at the same time

27 47%

23 40%

21 36%

19 33%

19 33%

18 31%

15 26%

12 21%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause hyperglycaemia in dogs?: 58 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 12 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperglycaemia with similar medicines

Hyperglycaemia after Melarsomine (Immiticide) 150 reports · 0.7% of its reports
Hyperglycaemia after Diphenhydramine 74 reports · 1.6% of its reports
Hyperglycaemia after Butorphanol 74 reports · 1.7% of its reports
Hyperglycaemia after Cefpodoxime 49 reports · 1.2% of its reports
Hyperglycaemia after Tramadol 64 reports · 1.7% of its reports
Hyperglycaemia after Florfenicol + Mometasone + Terbinafine 26 reports · 0.7% of its reports
Hyperglycaemia after Desoxycorticosterone Pivalate 33 reports · 1.0% of its reports
Hyperglycaemia after Propofol 41 reports · 1.3% of its reports
Hyperglycaemia after Dirlotapide 35 reports · 1.2% of its reports
Hyperglycaemia after Isoflurane 38 reports · 1.4% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with hyperglycaemia