Hyperglycaemia after Melarsomine (Immiticide) in dogs

150 reports to the FDA describe hyperglycaemia in dogs given Melarsomine. That is 0.7% of all reports for this medicine, compared with 0.5% across reports for all dog medicines.

150Reports

61%Marked serious

10%Recovered

17%Died or euthanised

21 daysTypical onset

How soon it started

Same day

10 11%

1–2 days

5 5.4%

3–7 days

23 25%

1–4 weeks

16 17%

Over a month

38 41%

How the animals did

Recovered

14 9.3%

Recovered with lasting effects

1 0.7%

Still unwell when reported

37 25%

Died

18 12%

Euthanised

8 5.3%

Not known

72 48%

Problems reported at the same time

110 73%

74 49%

47 31%

42 28%

42 28%

41 27%

35 23%

31 21%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause hyperglycaemia in dogs?: 150 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperglycaemia with similar medicines

Hyperglycaemia after Polysulfated Glycosaminoglycan 58 reports · 1.1% of its reports
Hyperglycaemia after Diphenhydramine 74 reports · 1.6% of its reports
Hyperglycaemia after Butorphanol 74 reports · 1.7% of its reports
Hyperglycaemia after Cefpodoxime 49 reports · 1.2% of its reports
Hyperglycaemia after Tramadol 64 reports · 1.7% of its reports
Hyperglycaemia after Florfenicol + Mometasone + Terbinafine 26 reports · 0.7% of its reports
Hyperglycaemia after Desoxycorticosterone Pivalate 33 reports · 1.0% of its reports
Hyperglycaemia after Propofol 41 reports · 1.3% of its reports
Hyperglycaemia after Dirlotapide 35 reports · 1.2% of its reports
Hyperglycaemia after Isoflurane 38 reports · 1.4% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with hyperglycaemia