Collapse after Polysulfated Glycosaminoglycan in dogs

The FDA has received 129 reports of collapse in dogs after Polysulfated Glycosaminoglycan. That is 2.4% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

129Reports
66%Marked serious
19%Recovered
39%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
26 38%
1–2 days
7 10%
3–7 days
6 8.7%
1–4 weeks
14 20%
Over a month
16 23%

How the animals did

Recovered
24 19%
Still unwell when reported
21 16%
Died
31 24%
Euthanised
19 15%
Not known
34 26%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
4
4–7 years
12
8–11 years
53
12+ years
56

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause collapse in dogs?
129 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Collapse with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with collapse