Abnormal ultrasound finding after Polysulfated Glycosaminoglycan in dogs

118 reports to the FDA describe abnormal ultrasound finding in dogs given Polysulfated Glycosaminoglycan. That is 2.2% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

118Reports

75%Marked serious

9.3%Recovered

34%Died or euthanised

34 daysTypical onset

How soon it started

Same day

10 17%

1–2 days

0 0.0%

3–7 days

5 8.5%

1–4 weeks

13 22%

Over a month

31 53%

How the animals did

Recovered

9 7.6%

Recovered with lasting effects

2 1.7%

Still unwell when reported

36 31%

Died

13 11%

Euthanised

27 23%

Not known

31 26%

Problems reported at the same time

61 52%

57 48%

54 46%

48 41%

41 35%

34 29%

25 21%

23 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause abnormal ultrasound finding in dogs?: 118 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 34 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

Abnormal ultrasound finding after Melarsomine (Immiticide) 64 reports · 0.3% of its reports
Abnormal ultrasound finding after Diphenhydramine 87 reports · 1.8% of its reports
Abnormal ultrasound finding after Butorphanol 96 reports · 2.2% of its reports
Abnormal ultrasound finding after Cefpodoxime 114 reports · 2.8% of its reports
Abnormal ultrasound finding after Tramadol 189 reports · 5.0% of its reports
Abnormal ultrasound finding after Desoxycorticosterone Pivalate 35 reports · 1.0% of its reports
Abnormal ultrasound finding after Propofol 61 reports · 2.0% of its reports
Abnormal ultrasound finding after Isoflurane 74 reports · 2.7% of its reports
Abnormal ultrasound finding after Cephalexin 47 reports · 1.8% of its reports
Abnormal ultrasound finding after Atipamezole 33 reports · 1.2% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with abnormal ultrasound finding