Permethrin + Pyriproxyfen side effects in dogs

487 reports sent to the FDA between 2011 and 2026 involve Permethrin + Pyriproxyfen in dogs. The most reported problems were vomiting, lethargy, loss of appetite. 29% were marked serious.

487Reports
29%Marked serious
0.0%Only medicine involved
32%Recovered
5.1%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

129 26%
98 20%
51 10%
34 7.0%
34 7.0%
28 5.7%
Allergic reaction
19 3.9%
Breathing problems
19 3.9%
Blood problems
18 3.7%
Fever
17 3.5%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
19 3.9%
Didn't stop ticks
9 1.8%

How soon problems started

Same day
70 23%
1–2 days
30 9.9%
3–7 days
22 7.2%
1–4 weeks
31 10%
Over a month
151 50%

Time from the first dose to the first sign, where both dates were reported (304 reports).

How the animals did

Recovered
154 32%
Recovered with lasting effects
3 0.6%
Still unwell when reported
138 28%
Died
7 1.4%
Euthanised
18 3.7%
Not known
167 34%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other medicines for dogs