Itching after Permethrin + Pyriproxyfen in dogs

34 reports to the FDA describe itching in dogs given Permethrin + Pyriproxyfen. That is 7.0% of all reports for this medicine, compared with 4.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

34Reports
41%Marked serious
41%Recovered
5.9%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
10 40%
1–2 days
5 20%
3–7 days
0 0.0%
1–4 weeks
1 4.0%
Over a month
9 36%

How the animals did

Recovered
14 41%
Still unwell when reported
11 32%
Euthanised
2 5.9%
Not known
7 21%

Problems reported at the same time

Breathing problems
6 18%
Restlessness or agitation
6 18%
Collapse
4 12%
Allergic reaction
4 12%
Skin redness
4 12%

Age of the animals

Under 1 year
5
1–3 years
12
4–7 years
10
8–11 years
6
12+ years
0

About this medicine

Type: medicine.

Questions owners ask

Can Permethrin + Pyriproxyfen cause itching in dogs?
34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Itching with similar medicines

All reported side effects of Permethrin + Pyriproxyfen in dogs · Medicines most reported with itching