Seizures after Permethrin + Pyriproxyfen in dogs

28 reports to the FDA describe seizures in dogs given Permethrin + Pyriproxyfen. That is 5.7% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

28Reports
86%Marked serious
43%Recovered
14%Died or euthanised
23 daysTypical onset
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How soon it started

Same day
5 24%
1–2 days
2 9.5%
3–7 days
3 14%
1–4 weeks
3 14%
Over a month
8 38%

How the animals did

Recovered
12 43%
Still unwell when reported
8 29%
Euthanised
4 14%
Not known
4 14%

Problems reported at the same time

4 14%
4 14%
Drooling
3 11%
Weakness
3 11%

Age of the animals

Under 1 year
0
1–3 years
10
4–7 years
7
8–11 years
4
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Permethrin + Pyriproxyfen cause seizures in dogs?
28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 23 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Permethrin + Pyriproxyfen in dogs · Medicines most reported with seizures