Overdose after Oclacitinib (Apoquel) in dogs

806 reports to the FDA describe overdose in dogs given Oclacitinib. That is 2.8% of all reports for this medicine, compared with 1.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

806Reports
32%Marked serious
11%Recovered
2.7%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
199 39%
1–2 days
78 15%
3–7 days
33 6.5%
1–4 weeks
46 9.0%
Over a month
154 30%

How the animals did

Recovered
87 11%
Recovered with lasting effects
2 0.2%
Still unwell when reported
602 75%
Died
11 1.4%
Euthanised
11 1.4%
Not known
93 12%

Problems reported at the same time

Age of the animals

Under 1 year
17
1–3 years
151
4–7 years
283
8–11 years
216
12+ years
107

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause overdose in dogs?
806 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Overdose with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with overdose