Accidental exposure after Oclacitinib (Apoquel) in dogs

The FDA has received 211 reports of accidental exposure in dogs after Oclacitinib. That is 0.7% of all reports for this medicine, compared with 1.5% across reports for all dog medicines, so it is reported less often than average with this medicine.

211Reports

46%Marked serious

16%Recovered

3.3%Died or euthanised

Same dayTypical onset

How soon it started

Same day

119 62%

1–2 days

45 23%

3–7 days

5 2.6%

1–4 weeks

6 3.1%

Over a month

17 8.9%

How the animals did

Recovered

33 16%

Still unwell when reported

144 68%

Died

2 0.9%

Euthanised

5 2.4%

Not known

27 13%

Problems reported at the same time

150 71%

71 34%

56 27%

37 18%

25 12%

23 11%

19 9.0%

Third eyelid protrusion

18 8.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause accidental exposure in dogs?: 211 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Accidental exposure with similar medicines

Accidental exposure after Cyclosporine (Atopica) 54 reports · 0.4% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with accidental exposure