Tachycardia after Oclacitinib (Apoquel) in dogs

166 reports to the FDA describe tachycardia in dogs given Oclacitinib. That is 0.6% of all reports for this medicine, compared with 0.5% across reports for all dog medicines.

166Reports

78%Marked serious

19%Recovered

22%Died or euthanised

Same dayTypical onset

How soon it started

Same day

71 52%

1–2 days

18 13%

3–7 days

3 2.2%

1–4 weeks

19 14%

Over a month

26 19%

How the animals did

Recovered

31 19%

Still unwell when reported

73 44%

Died

15 9.0%

Euthanised

21 13%

Not known

26 16%

Problems reported at the same time

81 49%

61 37%

53 32%

46 28%

42 25%

38 23%

37 22%

36 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause tachycardia in dogs?: 166 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tachycardia with similar medicines

Tachycardia after Cyclosporine (Atopica) 103 reports · 0.7% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with tachycardia