Loss of appetite after Oclacitinib (Apoquel) in dogs

2,571 reports to the FDA describe loss of appetite in dogs given Oclacitinib. That is 8.9% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.

2,571Reports
45%Marked serious
17%Recovered
15%Died or euthanised
12 daysTypical onset
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How soon it started

Same day
381 20%
1–2 days
279 15%
3–7 days
213 11%
1–4 weeks
339 18%
Over a month
712 37%

How the animals did

Recovered
430 17%
Recovered with lasting effects
4 0.2%
Still unwell when reported
1,401 54%
Died
112 4.4%
Euthanised
263 10%
Not known
361 14%

Problems reported at the same time

Age of the animals

Under 1 year
23
1–3 years
440
4–7 years
813
8–11 years
856
12+ years
386

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause loss of appetite in dogs?
2,571 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 12 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with loss of appetite