Vomiting after Oclacitinib (Apoquel) in dogs

4,027 reports to the FDA describe vomiting in dogs given Oclacitinib. That is 14% of all reports for this medicine, compared with 28% across reports for all dog medicines, so it is reported less often than average with this medicine.

4,027Reports
32%Marked serious
34%Recovered
8.1%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
1,026 32%
1–2 days
459 14%
3–7 days
311 9.8%
1–4 weeks
468 15%
Over a month
906 29%

How the animals did

Recovered
1,353 34%
Recovered with lasting effects
7 0.2%
Still unwell when reported
1,725 43%
Died
127 3.2%
Euthanised
198 4.9%
Not known
617 15%

Problems reported at the same time

Age of the animals

Under 1 year
64
1–3 years
963
4–7 years
1,265
8–11 years
1,123
12+ years
450

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause vomiting in dogs?
4,027 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with vomiting