Vomiting after Ilunocitinib (Zenrelia) in dogs

The FDA has received 295 reports of vomiting in dogs after Ilunocitinib. That is 13% of all reports for this medicine, compared with 28% across reports for all dog medicines, so it is reported less often than average with this medicine.

295Reports

40%Marked serious

33%Recovered

16%Died or euthanised

25 daysTypical onset

How soon it started

Same day

39 15%

1–2 days

35 14%

3–7 days

25 9.7%

1–4 weeks

40 16%

Over a month

119 46%

How the animals did

Recovered

96 33%

Still unwell when reported

77 26%

Died

13 4.4%

Euthanised

34 12%

Not known

75 25%

Problems reported at the same time

108 37%

99 34%

96 33%

70 24%

46 16%

34 12%

31 11%

31 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

103

8–11 years

12+ years

About this medicine

Ilunocitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Zenrelia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Ilunocitinib cause vomiting in dogs?: 295 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 25 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

Vomiting after Oclacitinib (Apoquel) 4,027 reports · 14% of its reports
Vomiting after Cyclosporine (Atopica) 5,694 reports · 37% of its reports

All reported side effects of Ilunocitinib in dogs · Medicines most reported with vomiting