Inappropriate schedule of drug administration after Oclacitinib (Apoquel) in dogs

593 reports to the FDA describe inappropriate schedule of drug administration in dogs given Oclacitinib. That is 2.0% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

593Reports

14%Marked serious

5.1%Recovered

0.5%Died or euthanised

43 daysTypical onset

How soon it started

Same day

38 15%

1–2 days

7 2.7%

3–7 days

12 4.7%

1–4 weeks

53 21%

Over a month

146 57%

How the animals did

Recovered

29 4.9%

Recovered with lasting effects

1 0.2%

Still unwell when reported

473 80%

Died

1 0.2%

Euthanised

2 0.3%

Not known

87 15%

Problems reported at the same time

Didn't work as expected

526 89%

83 14%

81 14%

33 5.6%

24 4.0%

23 3.9%

Drug administration error

23 3.9%

Diarrhea

20 3.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

209

8–11 years

195

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause inappropriate schedule of drug administration in dogs?: 593 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 43 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Oclacitinib in dogs · Medicines most reported with inappropriate schedule of drug administration