Diarrhea after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) in dogs
800 reports to the FDA describe diarrhea in dogs given Lufenuron + Milbemycin Oxime + Praziquantel. That is 8.0% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.
800Reports
44%Marked serious
39%Recovered
2.3%Died or euthanised
2 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Lufenuron stops flea eggs from developing. Milbemycin Oxime prevents heartworm and controls some intestinal worms (monthly). Praziquantel treats tapeworms.
Products with this combination include Sentinel Spectrum. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Lufenuron + Milbemycin Oxime + Praziquantel cause diarrhea in dogs?
- 800 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 2 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Diarrhea with similar medicines
- Diarrhea after Spinosad (Comfortis) 2,388 reports · 4.2% of its reports
- Diarrhea after Lufenuron + Milbemycin Oxime (Sentinel) 2,524 reports · 9.7% of its reports
- Diarrhea after Imidacloprid + Moxidectin (Advantage Multi) 1,203 reports · 9.2% of its reports
- Diarrhea after Nitenpyram (Capstar) 626 reports · 5.8% of its reports
- Diarrhea after Fipronil + S-methoprene (Frontline Plus) 230 reports · 7.8% of its reports
- Diarrhea after Flumethrin + Imidacloprid (Seresto) 130 reports · 5.7% of its reports
- Diarrhea after Imidacloprid 93 reports · 4.9% of its reports
- Diarrhea after Fipronil 123 reports · 8.7% of its reports
- Diarrhea after Lufenuron 182 reports · 18% of its reports
- Diarrhea after Imidacloprid + Permethrin + Pyriproxyfen 53 reports · 7.2% of its reports
All reported side effects of Lufenuron + Milbemycin Oxime + Praziquantel in dogs · Medicines most reported with diarrhea