Liver problems after Ampicillin in dogs

The FDA has received 356 reports of liver problems in dogs after Ampicillin. That is 36% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

356Reports
83%Marked serious
9.0%Recovered
57%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
49 17%
1–2 days
49 17%
3–7 days
62 21%
1–4 weeks
80 27%
Over a month
55 19%

How the animals did

Recovered
32 9.0%
Still unwell when reported
95 27%
Died
65 18%
Euthanised
137 38%
Not known
27 7.6%

Problems reported at the same time

Age of the animals

Under 1 year
29
1–3 years
58
4–7 years
104
8–11 years
106
12+ years
55

About this medicine

Type: medicine.

Questions owners ask

Can Ampicillin cause liver problems in dogs?
356 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Ampicillin in dogs · Medicines most reported with liver problems