Leucocytosis after Ampicillin in dogs

The FDA has received 145 reports of leucocytosis in dogs after Ampicillin. That is 15% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

145Reports
79%Marked serious
9.0%Recovered
56%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
24 20%
1–2 days
19 16%
3–7 days
28 23%
1–4 weeks
30 25%
Over a month
21 17%

How the animals did

Recovered
13 9.0%
Still unwell when reported
33 23%
Died
31 21%
Euthanised
50 34%
Not known
18 12%

Problems reported at the same time

Age of the animals

Under 1 year
24
1–3 years
26
4–7 years
42
8–11 years
38
12+ years
15

About this medicine

Type: medicine.

Questions owners ask

Can Ampicillin cause leucocytosis in dogs?
145 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

All reported side effects of Ampicillin in dogs · Medicines most reported with leucocytosis