Lethargy after Ampicillin in dogs

320 reports to the FDA describe lethargy in dogs given Ampicillin. That is 33% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

320Reports
80%Marked serious
8.1%Recovered
50%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
48 18%
1–2 days
46 17%
3–7 days
64 24%
1–4 weeks
55 21%
Over a month
51 19%

How the animals did

Recovered
26 8.1%
Still unwell when reported
99 31%
Died
55 17%
Euthanised
106 33%
Not known
34 11%

Problems reported at the same time

Age of the animals

Under 1 year
46
1–3 years
60
4–7 years
90
8–11 years
84
12+ years
34

About this medicine

Type: medicine.

Questions owners ask

Can Ampicillin cause lethargy in dogs?
320 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Ampicillin in dogs · Medicines most reported with lethargy