Elevated gamma-glutamyl transferase (ggt) after Ampicillin in dogs

The FDA has received 45 reports of elevated gamma-glutamyl transferase (ggt) in dogs after Ampicillin. That is 4.6% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

45Reports
80%Marked serious
2.2%Recovered
53%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
9 23%
1–2 days
3 7.5%
3–7 days
5 13%
1–4 weeks
12 30%
Over a month
11 28%

How the animals did

Recovered
1 2.2%
Still unwell when reported
17 38%
Died
8 18%
Euthanised
16 36%
Not known
3 6.7%

Problems reported at the same time

Liver problems
41 91%
Loss of appetite
27 60%
Lethargy
25 56%
Death
23 51%
Vomiting
23 51%
Kidney problems
19 42%
Abnormal ultrasound finding
17 38%
Blood problems
16 36%

Age of the animals

Under 1 year
3
1–3 years
7
4–7 years
11
8–11 years
14
12+ years
10

About this medicine

Type: medicine.

Questions owners ask

Can Ampicillin cause elevated gamma-glutamyl transferase (ggt) in dogs?
45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated gamma-glutamyl transferase (ggt) with similar medicines

All reported side effects of Ampicillin in dogs · Medicines most reported with elevated gamma-glutamyl transferase (ggt)