Elevated gamma-glutamyl transferase (ggt) after Cefpodoxime in dogs

The FDA has received 42 reports of elevated gamma-glutamyl transferase (ggt) in dogs after Cefpodoxime. That is 1.0% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

42Reports
52%Marked serious
2.4%Recovered
26%Died or euthanised
9 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
3 10%
1–2 days
6 21%
3–7 days
5 17%
1–4 weeks
7 24%
Over a month
8 28%

How the animals did

Recovered
1 2.4%
Still unwell when reported
21 50%
Died
4 9.5%
Euthanised
7 17%
Not known
9 21%

Problems reported at the same time

Liver problems
41 98%
Loss of appetite
24 57%
Vomiting
21 50%
Lethargy
16 38%
Kidney problems
16 38%
Death
11 26%
Weight loss
11 26%
Abnormal ultrasound finding
10 24%

Age of the animals

Under 1 year
2
1–3 years
2
4–7 years
16
8–11 years
14
12+ years
8

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause elevated gamma-glutamyl transferase (ggt) in dogs?
42 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated gamma-glutamyl transferase (ggt) with similar medicines

All reported side effects of Cefpodoxime in dogs · Medicines most reported with elevated gamma-glutamyl transferase (ggt)