Elevated gamma-glutamyl transferase (ggt) after Desoxycorticosterone Pivalate in dogs

26 reports to the FDA describe elevated gamma-glutamyl transferase (ggt) in dogs given Desoxycorticosterone Pivalate. That is 0.8% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports
58%Marked serious
0.0%Recovered
19%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
0 0.0%
1–2 days
1 10%
3–7 days
2 20%
1–4 weeks
3 30%
Over a month
4 40%

How the animals did

Still unwell when reported
6 23%
Died
1 3.8%
Euthanised
4 15%
Not known
15 58%

Problems reported at the same time

Liver problems
22 85%
Loss of appetite
10 38%
Lethargy
8 31%
Blood problems
6 23%
High sodium-potassium ratio (na:k ratio)
6 23%
Hypoalbuminaemia
5 19%
Leucocytosis
5 19%
Hyponatremia
5 19%

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
7
8–11 years
12
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause elevated gamma-glutamyl transferase (ggt) in dogs?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated gamma-glutamyl transferase (ggt) with similar medicines

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with elevated gamma-glutamyl transferase (ggt)