Dehydration after Emodepside + Praziquantel (Profender) in cats

87 reports to the FDA describe dehydration in cats given Emodepside + Praziquantel. That is 1.5% of all reports for this medicine, compared with 2.0% across reports for all cat medicines.

87Reports

78%Marked serious

25%Recovered

25%Died or euthanised

1 daysTypical onset

How soon it started

Same day

21 31%

1–2 days

25 37%

3–7 days

13 19%

1–4 weeks

6 9.0%

Over a month

2 3.0%

How the animals did

Recovered

22 25%

Still unwell when reported

6 6.9%

Died

10 11%

Euthanised

12 14%

Not known

37 43%

Problems reported at the same time

64 74%

55 63%

35 40%

23 26%

22 25%

19 22%

18 21%

17 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause dehydration in cats?: 87 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Praziquantel + Pyrantel 28 reports · 2.2% of its reports
Dehydration after Pyrantel 27 reports · 4.8% of its reports

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with dehydration