Blood problems after Emodepside + Praziquantel (Profender) in cats

43 reports to the FDA describe blood problems in cats given Emodepside + Praziquantel. That is 0.8% of all reports for this medicine, compared with 1.9% across reports for all cat medicines, so it is reported less often than average with this medicine.

43Reports
79%Marked serious
19%Recovered
33%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
7 20%
1–2 days
11 31%
3–7 days
4 11%
1–4 weeks
12 34%
Over a month
1 2.9%

How the animals did

Recovered
8 19%
Still unwell when reported
3 7.0%
Died
4 9.3%
Euthanised
10 23%
Not known
18 42%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
8
4–7 years
12
8–11 years
10
12+ years
5

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause blood problems in cats?
43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with blood problems