Fever after Emodepside + Praziquantel (Profender) in cats

The FDA has received 161 reports of fever in cats after Emodepside + Praziquantel. That is 2.8% of all reports for this medicine, compared with 3.2% across reports for all cat medicines.

161Reports

63%Marked serious

39%Recovered

6.8%Died or euthanised

1 daysTypical onset

How soon it started

Same day

48 39%

1–2 days

37 30%

3–7 days

21 17%

1–4 weeks

12 9.7%

Over a month

6 4.8%

How the animals did

Recovered

61 38%

Recovered with lasting effects

1 0.6%

Still unwell when reported

14 8.7%

Died

5 3.1%

Euthanised

6 3.7%

Not known

74 46%

Problems reported at the same time

105 65%

84 52%

39 24%

24 15%

18 11%

16 9.9%

15 9.3%

14 8.7%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause fever in cats?: 161 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

Fever after Praziquantel 26 reports · 1.6% of its reports
Fever after Praziquantel + Pyrantel 43 reports · 3.4% of its reports
Fever after Pyrantel 57 reports · 10% of its reports

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with fever