Liver problems after Vitamin K in dogs

The FDA has received 73 reports of liver problems in dogs after Vitamin K. That is 55% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

73Reports
92%Marked serious
9.6%Recovered
67%Died or euthanised
12 daysTypical onset
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How soon it started

Same day
9 14%
1–2 days
6 9.4%
3–7 days
11 17%
1–4 weeks
26 41%
Over a month
12 19%

How the animals did

Recovered
7 9.6%
Still unwell when reported
17 23%
Died
14 19%
Euthanised
35 48%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
13
4–7 years
29
8–11 years
22
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Vitamin K cause liver problems in dogs?
73 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 12 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Vitamin K in dogs · Medicines most reported with liver problems