Abnormal ultrasound finding after Vitamin K in dogs

The FDA has received 27 reports of abnormal ultrasound finding in dogs after Vitamin K. That is 20% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

27Reports

89%Marked serious

11%Recovered

74%Died or euthanised

13 daysTypical onset

How soon it started

Same day

2 9.5%

1–2 days

2 9.5%

3–7 days

1 4.8%

1–4 weeks

12 57%

Over a month

4 19%

How the animals did

Recovered

3 11%

Still unwell when reported

4 15%

Died

5 19%

Euthanised

15 56%

Problems reported at the same time

25 93%

21 78%

20 74%

19 70%

18 67%

11 41%

Hypoalbuminaemia

11 41%

Blood problems

9 33%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Vitamin K cause abnormal ultrasound finding in dogs?: 27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

Abnormal ultrasound finding after Melarsomine (Immiticide) 64 reports · 0.3% of its reports
Abnormal ultrasound finding after Polysulfated Glycosaminoglycan 118 reports · 2.2% of its reports
Abnormal ultrasound finding after Diphenhydramine 87 reports · 1.8% of its reports
Abnormal ultrasound finding after Butorphanol 96 reports · 2.2% of its reports
Abnormal ultrasound finding after Cefpodoxime 114 reports · 2.8% of its reports
Abnormal ultrasound finding after Tramadol 189 reports · 5.0% of its reports
Abnormal ultrasound finding after Desoxycorticosterone Pivalate 35 reports · 1.0% of its reports
Abnormal ultrasound finding after Propofol 61 reports · 2.0% of its reports
Abnormal ultrasound finding after Isoflurane 74 reports · 2.7% of its reports
Abnormal ultrasound finding after Cephalexin 47 reports · 1.8% of its reports

All reported side effects of Vitamin K in dogs · Medicines most reported with abnormal ultrasound finding