Swelling after Trilostane (Vetoryl) in dogs

149 reports to the FDA describe swelling in dogs given Trilostane. That is 1.2% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported less often than average with this medicine.

149Reports

81%Marked serious

15%Recovered

24%Died or euthanised

26 daysTypical onset

How soon it started

Same day

13 12%

1–2 days

10 8.8%

3–7 days

11 9.7%

1–4 weeks

26 23%

Over a month

53 47%

How the animals did

Recovered

23 15%

Still unwell when reported

36 24%

Died

8 5.4%

Euthanised

28 19%

Not known

54 36%

Problems reported at the same time

41 28%

37 25%

36 24%

33 22%

27 18%

25 17%

23 15%

Abnormal radiograph finding

22 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause swelling in dogs?: 149 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 26 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

Swelling after Insulin 107 reports · 1.5% of its reports
Swelling after Phenylpropanolamine (Proin) 71 reports · 1.7% of its reports
Swelling after Levothyroxine 82 reports · 2.7% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with swelling