Swelling after Insulin in dogs

The FDA has received 107 reports of swelling in dogs after Insulin. That is 1.5% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported less often than average with this medicine.

107Reports

50%Marked serious

26%Recovered

15%Died or euthanised

10 daysTypical onset

How soon it started

Same day

13 23%

1–2 days

8 14%

3–7 days

5 8.8%

1–4 weeks

10 18%

Over a month

21 37%

How the animals did

Recovered

20 19%

Recovered with lasting effects

8 7.5%

Still unwell when reported

31 29%

Died

8 7.5%

Euthanised

8 7.5%

Not known

32 30%

Problems reported at the same time

Loss of appetite

18 17%

Lethargy

17 16%

Didn't work as expected

16 15%

Death

16 15%

Vomiting

14 13%

Injection site reaction

11 10%

Allergic reaction

10 9.3%

Kidney problems

10 9.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause swelling in dogs?: 107 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

Swelling after Trilostane (Vetoryl) 149 reports · 1.2% of its reports
Swelling after Phenylpropanolamine (Proin) 71 reports · 1.7% of its reports
Swelling after Levothyroxine 82 reports · 2.7% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with swelling