Skin disorders after Trilostane (Vetoryl) in dogs

98 reports to the FDA describe skin disorders in dogs given Trilostane. That is 0.8% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

98Reports

59%Marked serious

8.2%Recovered

7.1%Died or euthanised

51 daysTypical onset

How soon it started

Same day

1 1.4%

1–2 days

3 4.2%

3–7 days

4 5.6%

1–4 weeks

18 25%

Over a month

45 63%

How the animals did

Recovered

8 8.2%

Still unwell when reported

16 16%

Died

4 4.1%

Euthanised

3 3.1%

Not known

67 68%

Problems reported at the same time

26 27%

24 24%

23 23%

20 20%

17 17%

16 16%

Skin rash or irritation

13 13%

Didn't work as expected

13 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause skin disorders in dogs?: 98 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 51 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin disorders with similar medicines

Skin disorders after Levothyroxine 23 reports · 0.8% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with skin disorders