Didn't work as expected after Trilostane (Vetoryl) in dogs

The FDA has received 1,750 reports of didn't work as expected in dogs after Trilostane. That is 15% of all reports for this medicine, compared with 13% across reports for all dog medicines.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause didn't work as expected in dogs?

1,750 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 76 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

• Didn't work as expected after Insulin 3,834 reports · 52% of its reports
• Didn't work as expected after Phenylpropanolamine (Proin) 702 reports · 17% of its reports
• Didn't work as expected after Levothyroxine 421 reports · 14% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with didn't work as expected