Skin rash or irritation after Trilostane (Vetoryl) in dogs

230 reports to the FDA describe skin rash or irritation in dogs given Trilostane. That is 1.9% of all reports for this medicine, compared with 1.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

230Reports
72%Marked serious
10%Recovered
10%Died or euthanised
30 daysTypical onset
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How soon it started

Same day
7 3.9%
1–2 days
12 6.7%
3–7 days
14 7.8%
1–4 weeks
57 32%
Over a month
89 50%

How the animals did

Recovered
22 9.6%
Recovered with lasting effects
1 0.4%
Still unwell when reported
57 25%
Died
8 3.5%
Euthanised
16 7.0%
Not known
126 55%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
35
8–11 years
123
12+ years
68

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause skin rash or irritation in dogs?
230 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 30 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin rash or irritation with similar medicines

All reported side effects of Trilostane in dogs · Medicines most reported with skin rash or irritation