Pain after Trilostane (Vetoryl) in dogs

108 reports to the FDA describe pain in dogs given Trilostane. That is 0.9% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

108Reports

76%Marked serious

9.3%Recovered

32%Died or euthanised

45 daysTypical onset

How soon it started

Same day

2 2.6%

1–2 days

7 9.2%

3–7 days

7 9.2%

1–4 weeks

18 24%

Over a month

42 55%

How the animals did

Recovered

9 8.3%

Recovered with lasting effects

1 0.9%

Still unwell when reported

19 18%

Died

4 3.7%

Euthanised

31 29%

Not known

44 41%

Problems reported at the same time

44 41%

39 36%

35 32%

32 30%

21 19%

18 17%

18 17%

18 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause pain in dogs?: 108 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 45 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pain with similar medicines

Pain after Insulin 43 reports · 0.6% of its reports
Pain after Phenylpropanolamine (Proin) 28 reports · 0.7% of its reports
Pain after Levothyroxine 28 reports · 0.9% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with pain