Pain after Levothyroxine in dogs

28 reports to the FDA describe pain in dogs given Levothyroxine. That is 0.9% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

28Reports

86%Marked serious

18%Recovered

39%Died or euthanised

67 daysTypical onset

How soon it started

Same day

2 11%

1–2 days

1 5.6%

3–7 days

3 17%

1–4 weeks

1 5.6%

Over a month

11 61%

How the animals did

Recovered

4 14%

Recovered with lasting effects

1 3.6%

Still unwell when reported

7 25%

Euthanised

11 39%

Not known

5 18%

Problems reported at the same time

12 43%

11 39%

11 39%

10 36%

6 21%

6 21%

6 21%

5 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Levothyroxine treats an underactive thyroid.

Questions owners ask

Can Levothyroxine cause pain in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 67 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pain with similar medicines

Pain after Trilostane (Vetoryl) 108 reports · 0.9% of its reports
Pain after Insulin 43 reports · 0.6% of its reports
Pain after Phenylpropanolamine (Proin) 28 reports · 0.7% of its reports

All reported side effects of Levothyroxine in dogs · Medicines most reported with pain