Blood problems after Trilostane (Vetoryl) in dogs

252 reports to the FDA describe blood problems in dogs given Trilostane. That is 2.1% of all reports for this medicine, compared with 1.8% across reports for all dog medicines.

252Reports

72%Marked serious

3.2%Recovered

27%Died or euthanised

77 daysTypical onset

How soon it started

Same day

4 2.3%

1–2 days

7 4.0%

3–7 days

17 9.8%

1–4 weeks

33 19%

Over a month

113 65%

How the animals did

Recovered

7 2.8%

Recovered with lasting effects

1 0.4%

Still unwell when reported

55 22%

Died

22 8.7%

Euthanised

47 19%

Not known

120 48%

Problems reported at the same time

119 47%

99 39%

94 37%

84 33%

69 27%

67 27%

62 25%

49 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

115

12+ years

115

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause blood problems in dogs?: 252 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 77 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

Blood problems after Insulin 89 reports · 1.2% of its reports
Blood problems after Phenylpropanolamine (Proin) 87 reports · 2.1% of its reports
Blood problems after Levothyroxine 104 reports · 3.5% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with blood problems