Liver problems after Tigilanol Tiglate in dogs

The FDA has received 99 reports of liver problems in dogs after Tigilanol Tiglate. That is 4.9% of all reports for this medicine, compared with 4.6% across reports for all dog medicines.

99Reports
96%Marked serious
18%Recovered
31%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
33 36%
1–2 days
24 26%
3–7 days
19 21%
1–4 weeks
8 8.7%
Over a month
8 8.7%

How the animals did

Recovered
18 18%
Still unwell when reported
13 13%
Died
10 10%
Euthanised
21 21%
Not known
37 37%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
18
8–11 years
56
12+ years
23

About this medicine

Type: medicine.

Questions owners ask

Can Tigilanol Tiglate cause liver problems in dogs?
99 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Tigilanol Tiglate in dogs · Medicines most reported with liver problems