Injection site reaction after Tigilanol Tiglate in dogs

The FDA has received 1,148 reports of injection site reaction in dogs after Tigilanol Tiglate. That is 57% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,148Reports

72%Marked serious

29%Recovered

7.8%Died or euthanised

1 daysTypical onset

How soon it started

Same day

394 37%

1–2 days

332 32%

3–7 days

168 16%

1–4 weeks

113 11%

Over a month

44 4.2%

How the animals did

Recovered

327 28%

Recovered with lasting effects

11 1.0%

Still unwell when reported

93 8.1%

Died

38 3.3%

Euthanised

51 4.4%

Not known

628 55%

Problems reported at the same time

Swelling

767 67%

Didn't work as expected

516 45%

331 29%

307 27%

234 20%

223 19%

202 18%

188 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

389

8–11 years

500

12+ years

158

About this medicine

Type: medicine.

Questions owners ask

Can Tigilanol Tiglate cause injection site reaction in dogs?: 1,148 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Melarsomine (Immiticide) 3,290 reports · 15% of its reports
Injection site reaction after Polysulfated Glycosaminoglycan 263 reports · 4.8% of its reports
Injection site reaction after Diphenhydramine 398 reports · 8.4% of its reports
Injection site reaction after Butorphanol 479 reports · 11% of its reports
Injection site reaction after Cefpodoxime 81 reports · 2.0% of its reports
Injection site reaction after Tramadol 123 reports · 3.3% of its reports
Injection site reaction after Desoxycorticosterone Pivalate 165 reports · 4.9% of its reports
Injection site reaction after Propofol 170 reports · 5.5% of its reports
Injection site reaction after Isoflurane 126 reports · 4.6% of its reports
Injection site reaction after Cephalexin 31 reports · 1.2% of its reports

All reported side effects of Tigilanol Tiglate in dogs · Medicines most reported with injection site reaction