Lethargy after Spironolactone in dogs

43 reports to the FDA describe lethargy in dogs given Spironolactone. That is 22% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports
67%Marked serious
12%Recovered
23%Died or euthanised
20 daysTypical onset
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How soon it started

Same day
5 17%
1–2 days
1 3.4%
3–7 days
1 3.4%
1–4 weeks
9 31%
Over a month
13 45%

How the animals did

Recovered
5 12%
Still unwell when reported
21 49%
Died
4 9.3%
Euthanised
6 14%
Not known
7 16%

Problems reported at the same time

19 44%
11 26%
10 23%
Weakness
6 14%
Pancreatitis
6 14%

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
1
8–11 years
13
12+ years
27

About this medicine

Type: medicine.

Questions owners ask

Can Spironolactone cause lethargy in dogs?
43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 20 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Spironolactone in dogs · Medicines most reported with lethargy