Kidney problems after Spironolactone in dogs

The FDA has received 32 reports of kidney problems in dogs after Spironolactone. That is 16% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Type: medicine.

Questions owners ask

Can Spironolactone cause kidney problems in dogs?

32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 35 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

• Kidney problems after Melarsomine (Immiticide) 434 reports · 1.9% of its reports
• Kidney problems after Polysulfated Glycosaminoglycan 319 reports · 5.8% of its reports
• Kidney problems after Diphenhydramine 221 reports · 4.7% of its reports
• Kidney problems after Butorphanol 203 reports · 4.6% of its reports
• Kidney problems after Cefpodoxime 248 reports · 6.1% of its reports
• Kidney problems after Tramadol 441 reports · 12% of its reports
• Kidney problems after Florfenicol + Mometasone + Terbinafine 52 reports · 1.5% of its reports
• Kidney problems after Desoxycorticosterone Pivalate 253 reports · 7.6% of its reports
• Kidney problems after Propofol 143 reports · 4.7% of its reports
• Kidney problems after Dirlotapide 78 reports · 2.8% of its reports

All reported side effects of Spironolactone in dogs · Medicines most reported with kidney problems