Selegiline (Anipryl) side effects in dogs

4,119 reports sent to the FDA between 1997 and 2026 involve Selegiline in dogs. The most reported problems were vomiting, restlessness or agitation, diarrhea. 1.6% were marked serious, and where it was recorded, signs eased after stopping the medicine in 100% of cases.

4,119Reports
1.6%Marked serious
95%Only medicine involved
1.1%Recovered
8.7%Died or euthanised
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About this medicine

Selegiline treats canine cognitive dysfunction.

Products with this ingredient include Anipryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
1 0.0%

How soon problems started

Same day
43 23%
1–2 days
14 7.6%
3–7 days
22 12%
1–4 weeks
33 18%
Over a month
73 39%

Time from the first dose to the first sign, where both dates were reported (185 reports).

How the animals did

Recovered
45 1.1%
Still unwell when reported
101 2.5%
Died
345 8.4%
Euthanised
12 0.3%
Not known
3,616 88%

Breeds named most often

Popular breeds appear more often because there are more of them.

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