Excessive urination after Selegiline (Anipryl) in dogs

The FDA has received 158 reports of excessive urination in dogs after Selegiline. That is 3.8% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

158Reports

1.3%Marked serious

0.0%Recovered

5.7%Died or euthanised

–Typical onset

How the animals did

Still unwell when reported

2 1.3%

Died

8 5.1%

Euthanised

1 0.6%

Not known

147 93%

Problems reported at the same time

Excessive thirst

142 90%

Didn't work as expected

58 37%

Restlessness or agitation

19 12%

18 11%

16 10%

16 10%

15 9.5%

14 8.9%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Selegiline treats canine cognitive dysfunction.

Products with this ingredient include Anipryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Selegiline cause excessive urination in dogs?: 158 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

Excessive urination after Gabapentin 377 reports · 4.2% of its reports
Excessive urination after Fluoxetine 40 reports · 1.5% of its reports
Excessive urination after Trazodone 70 reports · 2.8% of its reports
Excessive urination after Clomipramine (Clomicalm) 45 reports · 3.0% of its reports

All reported side effects of Selegiline in dogs · Medicines most reported with excessive urination