Kidney problems after Selegiline (Anipryl) in dogs

158 reports to the FDA describe kidney problems in dogs given Selegiline. That is 3.8% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

158Reports

3.2%Marked serious

0.0%Recovered

20%Died or euthanised

–Typical onset

How the animals did

Still unwell when reported

4 2.5%

Died

31 20%

Euthanised

1 0.6%

Not known

122 77%

Problems reported at the same time

64 41%

42 27%

38 24%

32 20%

27 17%

Didn't work as expected

24 15%

Weight loss

22 14%

Diarrhea

19 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

126

About this medicine

Selegiline treats canine cognitive dysfunction.

Products with this ingredient include Anipryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Selegiline cause kidney problems in dogs?: 158 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Gabapentin 801 reports · 8.9% of its reports
Kidney problems after Fluoxetine 58 reports · 2.2% of its reports
Kidney problems after Trazodone 161 reports · 6.4% of its reports
Kidney problems after Clomipramine (Clomicalm) 60 reports · 4.0% of its reports

All reported side effects of Selegiline in dogs · Medicines most reported with kidney problems