Kidney problems after Clomipramine (Clomicalm) in dogs

60 reports to the FDA describe kidney problems in dogs given Clomipramine. That is 4.0% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

60Reports
18%Marked serious
0.0%Recovered
20%Died or euthanised
–Typical onset
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How the animals did

Still unwell when reported
5 8.3%
Died
10 17%
Euthanised
2 3.3%
Not known
43 72%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
15
4–7 years
15
8–11 years
16
12+ years
13

About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Clomipramine cause kidney problems in dogs?
60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Clomipramine in dogs · Medicines most reported with kidney problems