Death after Clomipramine (Clomicalm) in dogs

The FDA has received 63 reports of death in dogs after Clomipramine. That is 4.2% of all reports for this medicine, compared with 5.2% across reports for all dog medicines.

63Reports

24%Marked serious

0.0%Recovered

100%Died or euthanised

6 daysTypical onset

How soon it started

Same day

3 25%

1–2 days

3 25%

3–7 days

1 8.3%

1–4 weeks

4 33%

Over a month

1 8.3%

How the animals did

Died

57 90%

Euthanised

6 9.5%

Problems reported at the same time

24 38%

24 38%

21 33%

19 30%

15 24%

12 19%

9 14%

9 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Clomipramine cause death in dogs?: 63 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

Death after Gabapentin 1,511 reports · 17% of its reports
Death after Selegiline (Anipryl) 354 reports · 8.6% of its reports
Death after Fluoxetine 111 reports · 4.3% of its reports
Death after Trazodone 251 reports · 9.9% of its reports

All reported side effects of Clomipramine in dogs · Medicines most reported with death