Vomiting after Clomipramine (Clomicalm) in dogs

The FDA has received 304 reports of vomiting in dogs after Clomipramine. That is 20% of all reports for this medicine, compared with 28% across reports for all dog medicines.

304Reports
14%Marked serious
18%Recovered
6.3%Died or euthanised
20 daysTypical onset
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How soon it started

Same day
20 24%
1–2 days
6 7.3%
3–7 days
7 8.5%
1–4 weeks
11 13%
Over a month
38 46%

How the animals did

Recovered
56 18%
Still unwell when reported
30 9.9%
Died
16 5.3%
Euthanised
3 1.0%
Not known
199 65%

Problems reported at the same time

Age of the animals

Under 1 year
22
1–3 years
83
4–7 years
105
8–11 years
56
12+ years
25

About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Clomipramine cause vomiting in dogs?
304 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 20 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

All reported side effects of Clomipramine in dogs · Medicines most reported with vomiting